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Session II:
March 20, 2025

Array Tomography

Program for Session II

(Coming soon)

Thank you Sponsors! 

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Mariano Soiza-Reilly

Quantitative analysis of input-specific brain circuits with Array Tomography

Mariano is a biologist by formation from the University of Buenos Aires in Argentina, where he also got a PhD studying the effects of antipsychotic drugs during brain development on the rat dopamine system. In 2009 he moved to Boston to do a postdoc with Katie Commons at Boston Children’s Hospital to investigate the structural changes of brain serotonin circuits contributing to emotional control and stress responses. There, Mariano started applying Array Tomography to quantitatively analyze the fine architecture of brain circuits. Then, in 2013 he moved to Paris to work with Patricia Gaspar at Inserm to study neurodevelopmental vulnerability of cortico-limbic circuits in mood disorders. Since 2019, he heads the Laboratory of Brain Circuits and Mental Disorders at the Instituto de Fisiología, Biología Molecular y Neurociencias of the University of Buenos Aires and CONICET in Argentina. His team applies Array Tomography to uncover quantitative synaptic features that could be relevant to understand and treat brain disorders.

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Mark Terasaki

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Serial section EM with the Thermo Fisher Hydra PFIB / spin mill 

After an undergrad degree in Physics at UCLA, Mark got his PhD at Berkeley working on tissue culture cell biology in Harry Rubin's lab in 1983. Fluorescence microscopy was just starting and as a post doc, Mark  found and developed a fluorescent dye for the ER. With this dye, He found a relationship between ER and microtubules. In Tom Reese's lab, and in collaboration with Laurinda Jaffe, Mark used a related dye to label ER for the then new confocal microscopy. In Mark’s own lab at UConn Health Center, he worked mostly on imaging live echinoderm eggs / embryos. He  switched to serial section EM (Lichtman tape collector approach) around 10 years ago and is mostly looking at mouse tissues. 

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Josh Morgan

Image processing for array tomography

Josh Morgan is an assistant professor of Ophthalmology and Visual Science, Neuroscience, and Biomedical Engineering at Washington University in St. Louis. Josh uses light and electron microscopy to reconstruct the synaptic connections in visual neural circuits. Josh has also been involved in the development of custom code for acquiring, analyzing, and displaying array tomography data.

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